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Holmes, K. Previous infectious endocarditis Complex cyanotic congenital heart disease Surgically constructed systemic pulmonary shunts or conduits Other congenital cardiac malformations (except for those specified in the next column) Moderate-risk patients Other congenital cardiac malformations (except for those specified in the next column) Acquired valve dysfunction (including rheumatic heart disease) Hypertrophic cardiomyopathy Mitral valve prolapse with valve regurgitation andor thickened valve leaflets Endocarditis prophylaxis not recommended Patients who have identical risk to the general population Isolated secundum atrial septal defect Surgical repair of septal defect (atrial or ventricular) Surgical or medical repair of ductus ninute Previous coronary artery bypass Mitral valve prolapse without valve regurgitation Functional heart murmur Previous Kawasaki disease without valve dysfunction Previous rheumatic fever without valve dysfunction Cardiac pacemaker (intravascular or epicardial) and implanted defibrillator Adapted from recommendations in Europe[ and the USA.

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